Foredragsholder / Presenter

Navn / Name: Nathalie Zibrandtsen

Institution: Rigshospitalet

Afdeling / Department: Øjenafdelingen/ Department of Ophthalmology

E-mail:annanathalie@yahoo.com

Medforfattere / Co-authors:

Navn / Name: Lisbeth Sandfeld Nielsen

Institution: Rigshospitalet

Afdeling / Department: Øjenafdelingen/ Department of Ophthalmology

Navn / Name: John Thygesen

Institution: Rigshospitalet

Afdeling / Department: Øjenafdelingen/ Department of Ophthalmology

Navn / Name: Hanne Jensen

Institution: Glostrup Hospital

Afdeling / Department: Øjenafdelingen / Department of Ophthalmology

ABSTRACT

Congenital glaucoma in Denmark

Purpose: To evaluate the outcome of young patients operated for congenital glaucoma (CG) between 1980 and 2005 in Denmark.

Design: Retrospective study

Background: Congenital glaucoma is a sight threatening disease, which untreated may lead to blindness. The treatment is surgical. If operated early and successfully, patients can be without medical treatment, they have better visual acuity and fewer visual field defects. However, a close follow up to the surgical treatment is essential to ensure regulation of intraocular pressure, visual acuity, and amblyopic treatment. Most often, the visual acuity is satisfying; though significantly lower than compared to children without CG 1. In Denmark, the surgical procedure is maintained at Rigshospitalet, Copenhagen. The surgical methods are either trabeculotomy or trabeculectomy.

The incidence in Denmark is 5-10 new cases per year, which is approximately 0.01% of live births. The etiology is heterogenic and among other causes, some genetic variants lead to CG. Primary congenital glaucoma is the most frequent variant, with no other ophthalmologic or systemic affections. A large genetic group is Peter’s Anomaly, with affections in the anterior chamber of the eye.

The existing material at Rigshospitalet is unique due to the few operating surgeons through the years and the data have not been analysed so far.

Methods: A database of 170 patients with CG is created. Data concerning subtype of CG, operation type, time of operation, and visual acuity before and after operation are registered. Moreover, intraocular pressure, corneal measures, axial length, visual field, refractive errors, and evaluations of cup-disk ratio are registered.

Results: This pilot study precedes a Ph.D. concerning visual outcome of patients operated for congenital glaucoma. A follow up of the effects of the surgical intervention in children diagnosed with CG is presented.

1) Long-term results of surgery in childhood glaucoma. Alsheikheh A et al . Graefes Arch Clin Exp Ophthalmol (2007) 245: 195-203